Isotopically Labeled Compounds
Medchemexpress LLC Nintedanib-d8 | 1624587-87-6 | 99.9% | C31H25D8N5O4 | 1 MG
Nintedanib-d8 is deuterium labeled Nintedanib, a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC L-cysteine-d2 | 130633-02-2 | MFCD01073499 | 98.7% | 123.17 g/mol | C3H5D2NO2S | 5mg
L-Cysteine-d2 is the deuterium labeled L-Cysteine L-Cysteine is a conditionally essential amino acid which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S) glutathione and taurine L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1]
Medchemexpress LLC N-(tert-Butoxycarbonyl)-L-alanine-3,3,3-d3 | 161602-47-7 | MFCD00084110 | 99.0% | 192.23 | 25 MG
Boc-L-Ala-OH-d3 is a deuterium labeled form of Boc-L-Ala-OH, utilized as a tracer and internal standard in quantitative analysis. Its stable heavy isotopes are valuable for drug development, influencing pharmacokinetic and metabolic profiles.
- Isotopic purity of 99 atom % D
- Solid form
- Optical activity of [α]20/D -23°, c = 2 in acetic acid
- Melting point of 79-83 °C (lit.)
- Suitable for bio NMR techniques
- Used in peptide synthesis
- Functional group is Boc
- Mass shift of M+3
- Can be used as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories L-LEUCINE (2-13C, 99%; 15N, 95-99%), 0.5 G
L-LEUCINE (2-13C, 99%; 15N, 95-99%), 0.5 G
Cambridge Isotope Laboratories 2 2 3 3 4 4 5-HeptaCB (PCB-170) (13C12 99%) 40 /-2 ug/mL in nonane 1 2 mL
2 2 3 3 4 4 5-HeptaCB (PCB-170) (13C12 99%) 40 /-2 ug/mL in nonane 1 2 mL
Medchemexpress LLC D-Alanine-d7 | 2483831-62-3 | 99.0% | 96.14 | 1 MG
D-Alanine-d7 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Lenvatinib-15N,d4 | 00-00-0 | 98.0% | 431.87 g/mol | C21H15D4ClN315NO4 | 5 MG
Lenvatinib-15N,d4 is an isotopically labeled analogue of lenvatinib intended for use as an internal standard or tracer in analytical and pharmacokinetic studies. The compound contains 15N and four deuterium labels to facilitate sensitive and specific LC-MS/MS quantification while limiting isotopic overlap.
- Isotopically labeled with 15N and four deuteriums for use as an internal standard.
- Formulated for analytical and pharmacokinetic LC-MS/MS applications.
- High purity (98.01%) suitable for quantitative studies.
- Powder form with recommended cold storage for stability.
- Molecular weight 431.87 g/mol and molecular formula C21H15D4ClN315NO4.
Medchemexpress LLC Rofecoxib-d5 | 544684-93-7 | 319.39 | 500 UG
Rofecoxib-d5 is a deuterium-labeled variant of Rofecoxib, a potent and orally active COX-2 inhibitor. It exhibits high selectivity for COX-2 over human COX-1, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, respectively, and an over 1000-fold selectivity for COX-2 compared to human COX-1 in U937 cells and Chinese hamster ovary cells.
- Can be utilized as a tracer in various applications.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes like deuterium can influence the pharmacokinetic and metabolic profiles of compounds.
![Revvity Health Sciences Inc Deoxy-D-glucose, 2-[1-14C]-, Aqueous Solution, 1 mCi (37 MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/509048179.jpg-250.jpg)
Revvity Health Sciences Inc Deoxy-D-glucose, 2-[1-14C]-, Aqueous Solution, 1 mCi (37 MBq)
Deoxy-D-glucose, 2-[1-14C]-, Aqueous Solution, 1 mCi (37 MBq)
Selleck Chemical LLC Ethanolamine hydrochloride
Ethanolamine (2-Aminoethanol) is a viscous hygroscopic amino alcohol with an ammoniacal odor It is widely distributed in biological tissue and is a component of lecithin
Medchemexpress LLC 17:0-17:1-17:0 TG-d5 | 958760-74-2 | 99.9% | 852.41 | 1 MG
17:0-17:1-17:0 TG-d5 is a deuterium-labeled derivative of 17:0-17:1-17:0 TG, designed for research applications. This compound is primarily utilized as a tracer and internal standard in quantitative analytical techniques.
- Used as a tracer in research studies.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes to influence pharmacokinetic and metabolic profiles of drugs.